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Table 2 Comparison of clinicopathologic characteristics between HCC patients who experienced hepatic insufficiency or not after right hemi-hepatectomy

From: Safe standard remnant liver volume after hepatectomy in HCC patients in different stages of hepatic fibrosis

Characteristic Insufficiency (n = 30) No insufficiency (n = 55) χ2 (t test) P
Sex     
 Male 28 42 3.846 0.05
 Female 2 13   
HBsAg     
 Positive 20 36 0.013 0.91
 Negative 10 19   
Tumour number     
 Single 18 34 0.027 0.869
 Multiple 12 21   
Preoperative parameter
Age (year) 43.47 ± 9.09 45.38 ± 12.67 0.731 0.467
Platelet count (109/L) 243.08 ± 95.26 271.44 ± 79.10 1.390 0.171
Total bilirubin (μmol/l) 16.51 ± 6.88 14.97 ± 13.89 − 0.686 0.495
Albumin (g/L) 39.62 ± 4.93 38.74 ± 4.26 − 0.824 0.414
ALT (IU/L) 49.27 ± 24.15 43.49 ± 27.08 − 1.009 0.317
AST (IU/L) 94.43 ± 84.22 69.29 ± 44.26 − 1.808 0.074
Prothrombin time (s) 13.33 ± 1.25 12.61 ± 1.11 − 2.612 0.012*
Alpha-foetoprotein (μg/ml) 821.73 ± 516.56 742.67 ± 1267.02 − 0.405 0.686
Body surface area (m2) 1.99 ± 0.15 1.93 ± 0.17 − 1.465 0.148
Tumour size (cm) 12.10 ± 2.79 10.98 ± 4.06 − 1.499 0.138
Remnant liver volume (ml) 489.89 ± 177.39 586.16 ± 226.31 2.164 0.034*
SRLV (ml/m2) 238.25 ± 62.14 305.85 ± 103.35 3.762 0.000**
Child–Pugh classification     
 A 22 49 2.452 0.117
 B 8 6   
Intraoperative parameter
Blood loss (ml) 753.33 ± 623.52 687.27 ± 667.72 − 0.455 0.651
Postoperative parameter
Tumour capsule     
 Yes 25 49 0.174 0.676
 No 5 6   
Macrovascular invasion     
 Yes 26 39 2.679 0.102
 No 4 16   
Hepatic fibrosis stage    6.863 0.032*
 No significant fibrosis 7 24   
 Severe fibrosis 7 17   
 Cirrhosis 16 14   
Hospital stay (days) 27.37 ± 7.78 25.51 ± 5.39 − 1.785 0.069
  1. Values are n (%) or mean ± SD, unless otherwise noted, *p < 0.05, **p < 0.01
  2. HBsAg hepatitis B surface antigen, ALT alanine transaminase, AST aspartate aminotransferase, BSA body surface area, SRLV standard remnant liver volume